- Dimitri Uznadze (December 2, 1886 - October 9, 1950) was a famous Georgian psychologist, philosopher and public benefactor, founder of the Georgian scientific school of Psychology, co-founder of the Tbilisi State University (TSU), Academician and co-founder of the Georgian Academy of Sciences (GAS),Meritorious Science Worker of Georgia, Dr.Sci., Professor.
- Evgeny Abramyan (born 1930), Soviet/Armenian physicist, Professor, Doctor of Engineering Sciences, Winner of USSR State Prize, one of the founders of several research directions in the Soviet and Russian nuclear technology
- Dr. Yona Kosashvili (born July 3, 1970) is a Georgian-born Israeli chess Grandmaster and surgeon. He was born in Tbilisi, Georgia, moved to Israel as a child. Yona Kosashvili is one of the few people in the world to have earned the titles MD and GM. He is an orthopedic surgeon, specializing in a variety of procedures including arthroscopy and total joint replacement. Dr. Kosashvili is actively involved in academics through his role as Clinical Instructor of Orthopedic Surgery at the University of Tel Aviv.
- Michel Tamarati, born Tamarashvili (September 1858 – September 16, 1911) was a Georgian Roman Catholic priest and historian, known for his oft-cited French-language history of the Georgian Christianity L'Eglise géorgienne des origines jusqu' à nos jours published in Rome in 1910. He died while trying to rescue a drowning man in stormy sea near Santa Marinella, Italy.
- Kita "Petre" Chkhenkeli (Georgian: კიტა "პეტრე" ჩხენკელი) (November 8, 1895 – October 22, 1963) was a Georgianlinguist and lexicographer based in Germany and Switzerland. He is best known for his Georgisch-Deutsches Wörterbuch, which is "widely regarded as the most comprehensive Georgian dictionary in any western language."